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CO-ADMINISTRATION SYNERGIQUE D'ANTIGENES REACTIFS A LARGE SPECTRE OPTIMISES PAR LE CALCUL POUR LA GRIPPE H5N1 HUMAINE ET AVIAIRE
- 专利权人:
- OREGON HEALTH & SCIENCE UNIVERSITY;SANOFI PASTEUR, INC.
- 发明人:
- ROSS, TED MILBURN,ALEFANTIS, TIM,CARTER, DONALD MARTIN, JR.,DARBY, CHRISTOPHER AUSTIN,KLEANTHOUS, HAROLD
- 申请号：
- CA2970163
- 公开号：
- CA2970163A1
- 申请日:
- 2015.12.18
- 申请国别(地区):
- CA
- 年份:
- 2016
- 代理人:
- 摘要：
- The present invention provides co-administration (e.g., immunogenic cocktail and/or prime-boost regimens) of computationally optimized H5N 1 influenza hemagglutinin (HA) polypeptides that. Co-administration of the optimized H5N 1 influenza hemagglutinin (HA) polypeptides facilitates synergistic neutralization of viral infection and provides for improved protective immunity (e.g., a broad reactive immune response) to multiple H5N 1 influenza virus clades and strains.
- 来源网站：
- 中国工程科技知识中心
- 来源网址：
- http://www.ckcest.cn/home/
