THERAPEUTIC COMBINATIONS COMPRISING ANTI-FOLR1 IMMUNOCONJUGATES

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专利权人:

IMMUNOGEN; INC.

发明人:

PONTE, JOSE,PINKAS, JAN,RUIZ-SOTO, RODRIGO R.

申请号：

CA2994888

公开号：

CA2994888A1

申请日:

2016.09.16

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

Therapeutic combinations of immunoconjugates that bind to FOLR1 (e.g., IMGN853) with anti-VEGF agents (e.g., bevacizumab), a platinum-based agent, and/or doxorubicin are provided. Methods of administering the combinations to treat cancers, e.g., ovarian cancers, with greater clinical efficacy and/or decreased toxicity are also provided.

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