A system and method is provided for deriving a pulse wave velocity-blood pressure (PWV-BP) transform. The method provides a general population PWV-BP transform comprising an average, population correlation of PWV measurements to BP measurements, where the selected average population shares common characteristics with a selected individual. The personal PWV-BP transform is based upon PWV and BP measurements for the first individual. If the personal PWV-BP transform is determined to be invalid, the general population PWV-BP is used to correlate the current PWV measurement for the first individual, to an estimated BP value for the first individual. The method modifies the general population PWV-BP transform using the at least a first PWV and BP measurement, and updates the general population PWV-BP transform. If a Sufficient number of simultaneous PWV and BP measurements are taken, and determined to be statistically valid, a personal PWV-BP transform can be established.