A balloon catheter includes a first outer tubular member, a second inner tubular member, an inflatable balloon, and a drug coating applied to at least a portion of the inflatable balloon. The inflatable balloon has opposing distal and proximal end portions. The inflatable balloon resides on the first and second tubular members in a twisted turn orientation of a pre-determined angle relative to the proximal end portion of the inflatable balloon attached to the first outer tubular member, such that the second inner tubular member achieves a constant torque of the balloon to twist and fold itself when retracted back into a portion of the first outer tubular member. Folds caused by the twisted turn orientation are configured and adapted to protect the drug coating while the inflatable balloon is deflated, thereby reducing premature drug elution and increasing the reliability and consistency of drug delivery.
