SMNDELTA7 DEGRON: NOVEL COMPOSITIONS AND METHODS OF USE

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专利权人:

发明人:

申请号：

EP10832087.0

公开号：

EP2501414A2

申请日:

2010.11.17

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention includes an isolated nucleic acid comprising a nucleic acid sequence encoding a SMN&Dgr7 degron and the encoded polypeptide. The invention also includes inhibitors of SMN&Dgr7 degron. The invention also includes compositions and methods for mitigating SMN deficiency by targeting inhibition of factors that mediate SMN&Dgr7-degron dependent degradation of SMN&Dgr7.

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中国工程科技知识中心

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