PUKYONG NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION
发明人:
Hyeung-Rak Kim
申请号：
US16176823
公开号：
US20200121747A1
申请日:
2018.10.31
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present disclosure relates to a pharmaceutical composition for the prevention or treatment of arthritis, the composition including a sargahydroquinoic acid as an active ingredient. The sargahydroquinoic acid according to the present disclosure has an excellent activity to reduce or inhibit the activity of IL-1β, IL-6, or TNF-α, which is an inflammatory cytokine, and has an excellent effect of ameliorating arthritis in an arthritis animal model, and thus can be advantageously used as a composition for the treatment of arthritis. In addition, the sargahydroquinoic acid causes neither drug toxicity and side effects, and thus can be safely used even when taken for a long period of time, and has a stable effect even in the body.
