PROBLEM TO BE SOLVED: To provide a combine harvester capable of improving attachment/detachment workability of an exhaust gas purification device 61 while easily securing a space for setting the exhaust gas purification device 61.SOLUTION: A combine harvester is structured as follows: an engine room frame 91 is set in parallel to a threshing device 5 an engine 14 is internally set in an engine room 92 formed of the engine room frame 91 an exhaust gas purification device 61 for treating exhaust gas from the engine 14 is equipped and the exhaust gas purification device 61 is connected to an exhaust pipe 116 of the engine 14. In the combine harvester, a sub-room frame 211 is formed to project toward the threshing device 5 from the side surface of the engine room frame 91, and the exhaust gas purification device 61 is fixedly placed on the sub-room frame 211.