One variation of the method for managing blood loss of a patient includes: receiving an image of a physical sample； extracting a feature from an area of the image corresponding to the physical sample； estimating a blood volume indicator of the physical sample according to the extracted feature； estimating a patient blood loss based on the blood volume indicator； estimating a euvolemic patient hematocrit based on an estimated patient blood volume and the estimated patient blood loss； receiving a measured patient hematocrit； and generating a volemic status indicator based on a comparison between the measured patient hematocrit and the estimated euvolemic patient hematocrit.
