A multi-use lancing device including a housing having a lancet opening and containing a supply reel, a storage reel, and a take-up reel, wherein the supply reel, the storage reel, and the take-up reel are each configured to rotate independently of the housing, an elongated flexible carrying tape configured for reel-to-reel transfer from the supply reel to the storage reel a plurality of lancets sequentially positioned along the carrying tape and each having a lancet length and a distal portion defining a sharp tip and a sterile removable cover over the lancets in the supply reel, where rotation of the take-up reel removes the cover from the lancets as the lancets are advanced from the supply reel to the storage reel.