The present invention provides (poly)peptides, which are recognized by human cytomegalovirus (CMV)-specific immune cells. The present invention further provides a combination of multiple CMV (poly)peptides, comprising at least two different groups of (poly)peptides according to the invention as well as conjugates, comprising said (poly)peptides and/or immune adjuvants thereof. Furthermore, this invention provides mixtures, comprising said (poly)peptides and/or immune cells (20) thereof, which are used to generate CMV-specific immune effector cells (31) with high sensitivity and specificity. In addition, the present invention provides a preparation method of CMV-specific immune effector cells (31), by using said (poly)peptides, adjuvants, immune cells (20) and/or mixtures thereof to generate anti-CMV immune response.本発明は、一種の免疫細胞を活性化する方法を提供する。これは、以下の、サイトメガロウイルス(CMV)由来のペプチドを含む免疫原組成物および免疫細胞を混合して混合培養物を形成するステップと、該混合培養物を適当な培地で培養するステップとを含み、これにより、活性化した免疫細胞が得られる。【選択図】図1
