The composition and method for the use of stabilized chlorine dioxide as an antimicrobial agent against oral microorganisms for the treatment and prevention of halitosis and prevention of oral diseases, wherein the activation and release of chlorine dioxide from the composition a) occurs rapidly and without a period of induction, b) results from the oxidative reduction and consumption of amino acids and volatile sulfur compound precursors, and c) generates twice the available chlorine dioxide gas as that generated from simply lowering the pH of the composition. The preferred concentrations of stabilized chlorine dioxide in this invention are in the range of 0.005% to 2.0% (w/v) wherein the pH of the composition is initially lowered by a citrate and then stabilized by a peroxy compound.揮発性硫黄化合物およびそれらのアミノ酸前駆体の酸化消耗および不活性化を通じて、安定化二酸化塩素を口臭の治療および予防のための、口腔内微生物に対する殺菌剤として使用するための組成物および方法が開示された。本発明の安定化二酸化塩素の好ましい濃度は0.005%から2.0%(w/v)の範囲である。【選択図】なし
