Jeffrey Dale Hartgerink,Vivek Ashok Kumar,Abhishek A. Jalan,I-Che Li
申请号:
US15449119
公开号:
US20170172953A1
申请日:
2017.03.03
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A composition and system for delivering a therapeutic agent is provided. The composition includes a self-assembling peptide ionically cross-linked with a charged therapeutic agent. In the presence of the charged therapeutic agent, the peptide self-assembles to form a nanofibrous hydrogel scaffold, wherein the hydrogel structure is quickly recoverable following a shear stress thereby permitting administration of the composition by syringe-needle or catheter injection. Methods of using the composition is also provided.