홍인기,문동수,조일지,박진수,이혜정,이윤진,장경희,신대현,박성훈,차윤정,HONG, IN KEEKR,MOON, DONG SOOKR,CHO, IL JEEKR,PARK, JIN SOOKR,LEE, HYE JEONGKR,LEE, YOON JINKR,JANG, KYOUNG HEEKR,SHIN, DAE HYUNKR,PARK, SUNG HOONKR,CHA, YOUN JEONG
申请号：
KR1020170006289
公开号：
KR1017873930000B1
申请日:
2017.01.13
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
The present invention relates to a culture solution ('cosmetic composition containing' red ginseng fermented product-skim milk culture solution ') obtained by inoculating and culturing mycelia of skimmed mushroom into fermented red ginseng fermented by inoculating a red ginseng powder with a mycelium of mycelia, The 'red ginseng fermented product-skimmer mushroom culture' of the present invention can be used for aquaporin-3, filaggrin, Increased expression of ceramide, increased hyaluronic acid production, reduced transdermal water loss, and increased water content resulted in excellent skin moisturizing effect and increased expression of VEGF (vascular endothelial cell growth factor) and PCNA (proliferation nuclear antigen) , Exhibits an excellent effect of increasing skin immunity, exhibits an effect of inhibiting NO production, inhibiting TNF-α production, and inhibiting PGE 2 production, thereby exerting an excellent effect of reducing skin irritation.본 발명은 홍삼 분말에 치마버섯 균사체 블록을 접종하여 발효시킨 홍삼 발효물에, 치마버섯 균사체를 접종하고 배양함으로써 수득되는 배양액(‘홍삼 발효물-치마버섯 배양액’을 함유하는 화장료 조성물에 관한 것으로, 본 발명의 ‘홍삼 발효물-치마버섯 배양액’은 아쿠아포린-3(Aquaporine-3), 필라그린(Filaggrin),세라마이드(Ceramide)발현 증가, 히알루론산 생성량 증가, 경피수분손실량 감소 및 수분함유량 증가효과를 나타내어 우수한 피부 보습 효과를 발휘하고, VEGF(혈관내피세포생장인자), PCNA(증식세포핵항원)의 발현을 증가시켜 우수한 피부 면역력 증가 효과를 발휘하며, NO 생성 억제, TNF-α 생성 억제, PGE2 생성 억제 효과를 나타내어 우수한 피부 염증 완화 효과를 발휘한다.
