A biopsy instrument driver includes a drive member having a laterally extending catch arm and movable between a distal, fired position and a proximal, armed position. A reversible motor has a rotatable output comprising or otherwise being operatively connected to a drive shaft, such that activation of the motor rotates the drive shaft. A translating member is threadably coupled to the drive shaft, wherein rotation of the drive shaft causes axial translation of the translating member along the drive shaft. A latch base is operatively associated with the translating member. A latch arm is pivotally coupled to the latch base, and has a distal portion configured to selectively engage and retain the drive member catch arm, and a proximal portion operatively coupled to the translating member, such that movement of the translating member relative to the latch base pivots latch arm distal portion.
