Mutant and infectious yellow fever virus cdna, DNA construct, recombinant yellow fever virus and human vaccine against yellow fever infections.

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专利权人:

FUNDAÇÃO OSWALDO CRUZ (FIOCRUZ)

发明人:

RICARDO GALLER,MARCOS DA SILVA FREIRE

申请号：

BR9701774

公开号：

BRPI9701774B1

申请日:

1997.04.11

申请国别(地区):

BR

年份:

2015

代理人:

摘要：

The present invention is related to a vaccine composition for humans against YF infections consisting essencially of a recombinant YF virus, YFiv5.2/DD, which is regenerated from YF infectious cDNA. There is provided new plasmids, pYF 5'3' IV/G1/2 and pYFM 5.2/T3/27, which together, have the complete sequence of said YF infectious cDNA. The method for producing recombinant YF virus and the Original, Primary and Secondary Seed Lots are other embodiments of the present invention. <；IMAGE>；

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