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NOUVEAU COMPOSÉ ET SON UTILISATION MÉDICALE
专利权人:
LTD.;ONO PHARMACEUTICAL CO.
发明人:
KOKUBO, MASAYA,YANO, KOJI
申请号:
EP11844106
公开号:
EP2647619A4
申请日:
2011.12.01
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
Provided is a levodopa prodrug that overcomes the problems attributed to the blood kinetics of levodopa such as large number of doses and the incidence of side effects due to frequent dosing. (2S)-2-Amino-3-(3,4-bis((2-(benzoyloxy)-2-methylpropanoyl)oxy)phenyl)propanoic acid, a salt thereof, or a solvate thereof is a levodopa prodrug, and provides a flat blood concentration-time profile of levodopa through oral administration, and therefore is useful as a preventive and/or therapeutic agent for Parkinson's disease and/or Parkinson's syndrome that overcomes the problems associated with pharmaceutical preparations of levodopa.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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