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Amide compounds useful in therapy
专利权人:
Pfizer Limited
发明人:
Gibson, Karl Richard,Green, Martin Peter,Underwood, Toby James,Wakenhut, Florian
申请号:
AU2009294290
公开号:
AU2009294290B2
申请日:
2009.09.16
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
A compound of Formula (I), or a pharmaceutically acceptable salt or solvate thereof, (I) wherein, R and R each independently represent H, halogen, CF, C alkyl or C alkoxy; R represents C alkyl, C cycloalkyl, phenyl (optionally substituted by one or more substituents each independently selected from R) or Het (optionally substituted by one or more substituents each independently selected from OH, oxo, or C alkyl); R represents H or C alkyl; R represents C alkyl (optionally substituted by one or more substituents each independently selected from R), Ccycloalkyl (optionally substituted by one or more substituents each independently selected from oxo or OH), or Het (optionally substituted by one or more substituents each independently selected from R); oxygen atom or 1 sulphur atom, or (c) 1 oxygen atom or 1 sulphur atom, (optionally substituted by one or more substituents each independently selected from OH, oxo or C alkyl); and R represents C alkyl (optionally substituted by one or more substituents each independently selected from R), Ccycloalkyl (optionally substituted by one or more halogen), CN or halogen; where R represents halogen or phenyl: and compositions, processes for the preparation, and uses thereof, e.g. in the treatment of endometriosis or uterine fibroids.
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