Columbia University;Yissum Research Development Company of The Hebrew University of Jerusalem LTD
发明人:
Saul Yedgar,Alice Prince,Yuval Cohen
申请号：
US14071578
公开号：
US20140100190A1
申请日:
2013.11.04
申请国别(地区):
US
年份:
2014
代理人:
摘要：
This invention provides for the use of compounds represented by the structure of the general formula (A):wherein L is a lipid or a phospholipid, Z is either nothing, ethanolamine, serine, inositol, choline, or glycerol, Y is either nothing or a spacer group ranging in length from 2 to 30 atoms, X is a physiologically acceptable monomer, dimer, oligomer, or polymer, wherein X is a glycosaminoglycan； and n is a number from 1 to 1000, wherein any bond between L, Z, Y and X is either an amide or an esteric bond in treating a subject suffering from cystic fibrosis, reducing or delaying the mortality of a subject suffering from cystic fibrosis or ameliorating symptoms associated with cystic fibrosis.
