Improvement is made in efficiency of positioning between images when comparing a plurality of images to perform a radiographic image interpretation in an image diagnosis assisting apparatus. An image diagnosis assisting apparatus, which assists an image diagnosis by use of registration among a plurality of images, comprises: a radiographic image interpretation terminal (104) for executing the registration; and storage devices (101, 103) for storing model images and the like to be used for the registration. The radiographic image interpretation terminal (104) executes the registration among the plurality of images by use of a positioning reference area, which was defined beforehand in a model image selected on the basis of both a purpose of checking the plurality of images and a part of interest and also by use of parameters of the registration determined on the basis of a manipulation of checking the plurality of images.