RNA-guided human genome engineering

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专利权人:

President and Fellows of Harvard College

发明人:

Prashant G. Mali,George M. Church,Luhan Yang

申请号：

US14319171

公开号：

US10717990B2

申请日:

2014.06.30

申请国别(地区):

US

年份:

2020

代理人:

摘要：

A method of altering a eukaryotic cell is provided including transfecting the eukaryotic cell with a nucleic acid encoding RNA complementary to genomic DNA of the eukaryotic cell, transfecting the eukaryotic cell with a nucleic acid encoding an enzyme that interacts with the RNA and cleaves the genomic DNA in a site specific manner, wherein the cell expresses the RNA and the enzyme, the RNA binds to complementary genomic DNA and the enzyme cleaves the genomic DNA in a site specific manner.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/