Compounds derived from quinazolinona tetrahydro -, Tank and parp-1 inhibitors; Preparation Process; Drugs; Pharmaceutical Kit, use in the treatment and / or prevention of cancer, multiple sclerosis, cardiovascular disease, central nervous system injury.
LEUTHNER, BIRGITTA,BUCHSTALLER, HANS-PETER,ESDAR, CHRISTINA
申请号:
CL2014002097
公开号:
CL2014002097A1
申请日:
2014.08.07
申请国别(地区):
CL
年份:
2014
代理人:
摘要:
Compounds of the formula I in which U, V and W have the meanings indicated in Claim 1, are inhibitors of Tankyrase, and can be employed, inter alia, for the treatment of diseases such as cancer, cardiovascular diseases, central nervous system injury and different forms of inflammation.55 COMPUESTOS ESPECÍFICOS DERIVADOS DE 5,6,7,8-TETRAHIDRO-3H-QUINAZOLINONA, INHIBIDORES DE TANK Y PARP-1; COMPOSICIÓN FARMACÉUTICA; KIT FARMACEUTICO; ÚTILES PARA EL TRATAMIENTO Y/O LA PREVENCION DEL CÁNCER, ESCLEROSIS MÚLTIPLE, ENFERMEDADES CARDIOVASCULARES, LESION DEL SISTEMA NERVIOSO CENTRAL.