Symatese;Universite Claude Bernard Lyon I;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS -;Centre National de la Recherche Scientifique - CNRS -
发明人:
ROUSSELLE, PATRICIA
申请号：
EP10715940.2
公开号：
EP2406275A1
申请日:
2010.03.15
申请国别(地区):
EP
年份:
2012
代理人:
摘要：
A peptide is provided with a defined sequence present in the alpha3 chain of the LG4 globule of laminin 332 (laminin 5), and peptides with sequences homologous to the peptide with the defined sequence capable of binding to the syndecan-1 receptor. Pharmaceutical or cosmetic compositions containing the peptide are provided. The peptide is used in the area of tissue healing and regeneration or as an adjuvant in culture media intended for epidermal or epithelial reconstruction. The synthetic peptide comprises the sequence KKLRIKSKEK (SEQ ID NO: 1) or a sequence of identical size, in which the K residue (in position 1) and the R residue (in position 4) are conserved, the sequence being able to bind to the syndecan-1 receptor.Peptide synthétique comprenant la séquence KKLRIKSKEK (SEQ ID 1) ou une séquence de taille identique, dans laquelle les résidus K (en position 1) et R (en position 4) sont conservés, la séquence étant apte à se lier au récepteur syndecan-1.
