Lawrence C. Horowitz,Ramesh R. Bhatt,Charles H. Hannum,Pamela K. Foreman,Danying Cai,Medini Gore,Li Xu,Phil Kobel
申请号:
US14979114
公开号:
US20160354486A1
申请日:
2015.12.22
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention concerns methods for identifying, producing, and engineering binding molecule conjugates, and to the conjugates produced. In particular, the invention concerns Surrobody conjugates composed of an antibody heavy chain variable domain and a surrogate light chain, wherein the surrogate light chain and/or the antibody heavy chain variable domain is conjugated to a therapeutic or diagnostic agent.