NICOUD, IAN B.,CLARKE, DOMINIC M.,MATTHEW, ABY J.,RICE, MICHAEL
申请号：
CA20092719825
公开号：
CA2719825(C)
申请日:
2009.03.27
申请国别(地区):
加拿大
年份:
2018
代理人:
摘要：
The present invention relates to materials and methods for hypothermic collection of whole blood, and components thereof, which can extend the holding time of blood beyond the current useable limit. Additionally, blood can be drawn directly into a hypothermic preservation solution without the addition of standard anticoagulants. This is enabled by providing sustained cellular viability under hypothermic conditions using a nutrient matrix devoid of animal proteins and containing energy substrates, free-radical scavengers, and impermeants that is ionically balanced for storage of biologic materials at low temperatures to prevent cellular stress-induced apoptosis.
