COMPOSITION, CONTAINING PROTAETIA BREVITARSIS EXTRACT OR COMPOUND ISOLATED THEREFROM AS ACTIVE INGREDIENT, FOR SKIN MOISTURIZATION OR SKIN WRINKLE RELIEF
KOREA INSTITUTE OF ORIENTAL MEDICINE;THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY
发明人:
CHAE, Sung Uk,IM, A-Rang,NA, Minkyun
申请号：
WO2018KR04158
公开号：
WO2018186724(A1)
申请日:
2018.04.09
申请国别(地区):
世界知识产权组织国际局
年份:
2018
代理人:
摘要：
The present invention relates to a composition, containing a Protaetia brevitarsis extract or a compound isolated therefrom as active ingredient, for skin moisturization or skin wrinkle relief. More specifically, the Protaetia brevitarsis extract and compounds of chemical formulas 1-5 have little cytotoxicity, significantly suppress MMP-1 and MMP-9 expressions promoted by ultraviolet irradiation, also reduce the skin thickness increased by ultraviolet irradiation, increase the content of hyaluronic acid capable of promoting skin moisturization, reduce the transdermal water loss, and increase the skin moisture content. Therefore, the composition of the present invention can be used as a health functional food composition for skin moisturization or wrinkle relief, or as a pharmaceutical composition for skin wrinkle relief or anti-aging action.
