SENJU PHARMACEUTICAL CO., LTD.;KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION;THE DOSHISHA
发明人:
KINOSHITA, SHIGERU,KOIZUMI, NORIKO,OKUMURA, NAOKI
申请号:
EP12862290
公开号:
EP2799537A4
申请日:
2012.12.27
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention provides a method for the normalized culturing ofcorneal endothelial cells. More specifically, the present invention provides a culture-normalizing-agent of a corneal endothelial cell, comprising a fibrosis inhibitor. In detail, the present invention provides a culture-normalizing agent comprising a transforming growth factor (TGF) ² signal inhibitor. The present invention also provides a culture medium for culturing a corneal endothelial cell normally, which comprises the culture-normalizing agent according to the present invention and corneal endothelium culture components. The present invention also provides a method for culturing a corneal endothelial cell normally, comprising the step of culturing a corneal endothelial cell using the culture-normalizing agent according to the present invention or the culture medium according to the present invention.