PEI, YANLONG,ACKFORD, JAMES,CORREDOR, JUAN CARLOS,KRELL, PETER J.,NAGY, EVA
申请号:
CA2991925
公开号:
CA2991925A1
申请日:
2016.07.11
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Described are recombinant viral vectors obtained from fowl adenovirus 9 (FAdV-9) and associated methods. The recombinant FAdV-9 vectors may include one or more deletions at the left end and/or right end of the FAdV-9 genome. Optionally, the vectors include one or more exogenous nucleotide sequences, such a sequences encoding for a polypeptide of interest. The recombinant FAdV-9 vectors may be used as a dual delivery vector. Also described is the use of the vectors for generating an immunogenic response in a subject and/or for the prevention of disease.