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SPIROINDOLINE DERIVATIVES FOR USE AS GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS
专利权人:
BAYER PHARMA AKTIENGESELLSCHAFT
发明人:
BÄURLE, Stefan,LANGER, Gernot,NOWAK-REPPEL, Katrin,NUBBEMEYER, Reinhard,PANKNIN, Olaf,RING, Sven,WAGENFELD, Andrea
申请号:
TN2015000453
公开号:
TN2015000453A1
申请日:
2014.04.08
申请国别(地区):
TN
年份:
2017
代理人:
摘要:
Spiroindoline derivatives, processes for their preparation and pharmaceutical compositions thereof, their use for the treatment of diseases, and their use for the manufacture of medicaments for the treatment of diseases, especially sex- hormone-related diseases in both men and women, in particularly those selected from the group of endometriosis, uterine leiomyoma (fibroids), polycystic ovarian disease, menorrhagia, dysmenorrhea, hirsutism, precocious puberty, gonadal steroid-dependent neoplasia such as cancers of the prostate, breast and ovary, gonadotrope pituitary adenomas, sleep apnea, irritable bowel syndrome, premenstrual syndrome, benign prostatic hypertrophy, contraception, infertility and assisted reproductive therapy such as in vitro fertilization. The present application relates in particular to spiroindoline derivatives as gonadotropin-releasing hormone (GnRH) receptor antagonists.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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