The invention relates to a combination product comprising: - a composition A comprising at least one filler product, and - a composition B comprising at least one chemically modified tetracycline, for the treatment of skin aging and scars, compositions A and B being used simultaneously, separately or sequentially over time. The invention also relates to a single pharmaceutical composition or a injectable fixed combination product comprising, in the same physiologically acceptable medium, at least one filler product and at least one chemically modified tetracycline.