De Goeij, Bart,Melis, Joost,Vink, Tom,Ten Napel, Hendrik,Breij, Esther,Satijn, David,Parren, Paul
申请号:
AU2017214338
公开号:
AU2017214338A1
申请日:
2017.02.03
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention relates to a multispecific antigen-binding molecule comprising a first antigen-binding domain and a second antigen-binding domain. The first domain specifically binds a target molecule (T), and the second domain specifically binds an internalizing effector protein (E), the second antigen-binding domain having a dissociation constant (K