PROCÉDÉ DE STABILISATION D'UN APTAMÈRE D'ADN

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专利权人:

TagCyx Biotechnologies

发明人:

HIRAO Ichiro,HIRAO Michiko,MATSUNAGA Kenichiro

申请号：

EP16761670

公开号：

EP3266871A4

申请日:

2016.03.04

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

An object of the present invention is to provide a convenient and low-cost method for enhancing the stability of a DNA aptamer and/or its capacity to bind to a target molecule, and a DNA aptamer obtained by the method. The object is solved by substituting an internal hairpin structure (stem-loop structure) of the DNA aptamer with a structure called mini-hairpin structure and optionally increasing GC pairs in a stem portion of the DNA aptamer.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/