Pia Runeberg-Roos;Richard Penn;Maxim M. Bespalov;Mart Saarma
发明人:
Richard Penn,Pia Runeberg-Roos,Maxim M. Bespalov,Mart Saarma
申请号：
US12946167
公开号：
US08445432B2
申请日:
2010.11.15
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Neurturin polypeptides which possess reduced heparin and heparan sulfate binding affinity but retain neurotrophic activity, nucleic acids which encode the neurturin variants and vectors and host cells which express the enhanced neurturin polypeptides. Use of the enhanced neurturin polypeptides, nucleic acids and host cells in the treatment or prevention of disease.
