PROBLEM TO BE SOLVED: To provide a biological observation apparatus capable of reducing a burden of an operator in a case of treating tumor tissues.SOLUTION: This biological observation apparatus is characterized by including a sound wave radiating unit that radiates a sound wave into an object to be examined in living tissue, an illumination light radiating unit that radiates illumination light capable of reaching the examination object, a light interfering unit that makes the illumination light interfere with light reflected from an area where the sound wave reaches and radiates interference light, a light detection unit that detects the interference light radiated from the light interfering unit and outputs it as an interference signal, and a calculation unit that calculates the amount of frequency modulation of the illumination light based on the interference signal and calculates a difference value between the two time-series adjacent amounts of frequency modulation in sequence.COPYRIGHT: (C)2009,JPO&INPIT【課題】腫瘍組織に対して処置を行う場合において、術者の負担を軽減可能な生体観測装置等を提供する。【解決手段】本発明の生体観測装置は、生体組織内部の検査対象部位に対して音波を出力する音波発生部と、検査対象部位に到達可能な照明光を出射する照明光発生部と、照明光が音波の到達領域において反射した反射光と照明光とを干渉させて生じた干渉光を出射する光干渉部と、光干渉部から出射される干渉光を検出し、干渉信号として出力する光検出部と、干渉信号に基づく照明光の周波数変調量を算出し、時系列的に隣接する2つの前記周波数変調量の差分値を順次算出する演算部と、を有することを特徴とする。【選択図】図1