University of Rochester Medical Centre;Androscience Corporation;University of North Carolina at Chapel Hill
发明人:
Lee, Kuo-Hsiung,Ishida, Junko,Ohtsu, Hironari,Wang, Hui-Kang,Itokawa, Hideji,Chang, Chawnshang,Shih, Charles C. Y.
申请号：
AU2009215207
公开号：
AU2009215207B2
申请日:
2009.09.14
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2009215207B220120705.pdf#####NOVEL CURCUMIN ANALOGUES AS USES THEREOF Abstract of the Disclosure The present invention relates to compounds capable of acting as androgen receptor antagonists, pharmaceutical formulations containing the same, and methods 5 of use thereof. Such uses include, but are not limited to, use as antitumor agents, particularly for the treatment of cancers such as colon, skin and prostate cancer and to induce androgen receptor antagonist activity in a subject afflicted with an androgenrelated affliction. Examples of androgen-related afflictions include, but are not limited to, baldness, hirsutism, behavioral disorders, acne, and uninhibited 10 spermatogenesis wherein inhibition of spermatogenesis is so desired. 828269_1 (GHMatters)
