Being the method of dealing with the acuteness, delayed fire characteristic or estimate characteristic vomiting of the continuous period in the individual, that method, i, the system the 5 HT3 receptor antagonist of the quantity which action is effective II, 0.5% of skin contact layer - 15 weight % including, the transmitted accelerator of the quantity which promotes the transmission which becomes And III, the composition of the adhesive, including the fact that it makes the portion of the intact skin of the individual apply, being the method of becoming, 12 hours when blood plasma density of the 5 HT3 receptor antagonist of the range where it is effective remedy in particular method, the particular composition is removed from start time between to after above, the method of being supplied is especially offered.個体における持続的期間の急性、遅発性または予測性嘔吐を処置する方法であって、その方法が、i、制吐作用的に有効な量の5-HT3受容体アンタゴニスト;ii、皮膚接触層の0.5%~15重量%を含んでなる透過を促進する量の透過促進剤;およびiii、接着剤の組成物を、個体の無傷の皮膚の一部に適用させることを含んでなる方法であって、当該方法において、治療的に有効な範囲の5-HT3受容体アンタゴニストの血漿濃度が、開始時間から当該組成物が除去された12時間以上後までの間、供給される方法が、とりわけ提供されている。
