Disclosed is a femoral resection guide for measuring and guiding resection of anterior portion and posterior portion of a femur and method thereof. The femoral resection guide comprises a front block, a rear block, a reference gauge means and a locking means. A main scale marked portion is provided corresponding to the front scale member and the rear scale member in order to obtain a size of a patients femur. The front block and the rear block are respectively provided with a resection guide surface for guiding a cutting tool to cut the femur. Moreover, the positions of the front resection guide surface and the rear resection guide surface in relation to the distal section of the femur can be adjusted, so that the problem of over or insufficient resection can be avoided, and the purchase cost and the storage space of the femoral resection instruments can be significantly reduced.
