KENNEDY, ADAM; INCORPORATED;CYTOKINETICS, INCORPORATED;JASPER, JEFFREY R.;HWEE, DARREN T.;MALIK, FADY;CYTOKINETICS
发明人:
MALIK, FADY,JASPER, JEFFREY, R.,KENNEDY, ADAM,HWEE, DARREN
申请号:
EP13775275
公开号:
EP2836590A4
申请日:
2013.04.11
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
Provided are compounds, compositions and methods for improving resistance to skeletal muscle fatigue comprising administering an effective amount of a skeletal muscle troponin activator. Also provided are methods for improving resistance to fatigue, improving physical endurance, or reducing exercise intolerance in a subject suffering from a condition associated with muscle fatigue or weakness, such as heart failure.