The present invention provides a recombinant varicella-zoster virus a process for producing the same a pharmacological composition containing a recombinant varicella-zoster virus a vector containing a genomic gene of varicella-zoster virus and BAC vector sequence cells containing the above vector a fragment capable of homologous recombination with a genome of varicella-zoster virus and a nucleic acid cassette containing the BAC vector sequence. For these, there is provided a process for producing a recombinant varicella-zoster virus, comprising use of the BAC vector sequence.
