DIOXYDES C2-AZASPIRO IMINOTHIAZINES EN TANT QU'INHIBITEURS DE BACE

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专利权人:

Merck Sharp & Dohme Corp.

发明人:

申请号：

EP14767603.5

公开号：

EP2968353B1

申请日:

2014.03.11

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

In its many embodiments, the present invention provides certain C2-azaspirosubstituted iminothiazine dioxide compounds. The novel compounds of the invention are useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including for the possible treatment of Alzheimer's disease, are also disclosed.

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