Considering the importance of the immunological checkpoint pathway in immune response control, we can adjust the activity of immunosuppressive proteins such as programmed death 1 (PD-1), which can be used for a novel combination therapy that causes the activation of the immune system Provides medication that can be used for other conditions.Solution: an antibody molecule that has a specific amino acid sequence and is capable of binding to PD-1 at least in part, high affinity and specificity, and can be used for treatment, prevention, and / or diagnosis of disorders due to cancer and disorders such as infections.No selection【課題】免疫応答制御における免疫チェックポイント経路の重要性を考慮して、プログラム死１(ＰＤ－１)などの免疫阻害性タンパク質の活性を調節し、免疫系の活性化をもたらす新規組み合わせ治療に使用可能な、例えば、癌免疫療法および慢性感染などの他の状態の処置にも使用できる薬剤の提供。【解決手段】特定のアミノ酸配列を有し、少なくとも一部、高親和性および特異性でＰＤ－１と結合し、癌による障害ならびに感染症などの障害の処置、予防および／または診断に使用できる抗体分子。【選択図】なし
