The present invention provides a therapeutic agent for hyperlipidemia having an excellent effect of lowering the cholesterol and triglyceride level in blood plasma. The present invention relates to a prophylactic and/or therapeutic agent for hyperlipidemia, a prophylactic and/or therapeutic agent for obesity or diabetes mellitus, and a prophylactic and/or therapeutic agent for metabolic syndrome, each agent including a compound represented by the following formula (1): , wherein,: R 1 and R 2 , which may be identical or different, each represent a hydrogen atom, a methyl group or an ethyl group； R 3 a, R 3 b, R 4 a and R 4 b, which may be identical or different, each represent a hydrogen atom, a halogen atom, a nitro group, a hydroxyl group, a C 1-4 alkyl group, a trifluoromethyl group, a C 1-4 alkoxy group, a C 1-4 alkylcarbonyloxy group, a di-C 1-4 alkylamino group, a C 1-4 alkylsulfonyloxy group, a C 1-4 alkylsulfonyl group, a C 1-4 alkylsulfinyl group, or a C 1-4 alkylthio group, or R 3 a and R 3 b, or R 4 a and R 4 b are joined to represent an alkylenedioxy group； X represents an oxygen atom, a sulfur atom or N-R 5 (wherein R 5 represents a hydrogen atom, a C 1-4 alkyl group, a C 1-4 alkylsulfonyl group, or a C 1-4 alkyloxycarbonyl group) ； Y represents an oxygen atom, a S(O) l group (l represents a number from 0 to 2), a carbonyl group, a carbonylamino group, an aminocarbonyl group, a sulfonylamino group, an aminosulfonyl group, or an NH group； Z represents CH or N； n represents a number from 1 to 6； and m represents a number from 2 to 6, or a salt thereof, anda statin, particularlypitavastatin, in combination.
