TRICYCLIC COMPOUNDS AS MPGES-1 INHIBITORS

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专利权人:

发明人:

GHARAT LAXMIKANT ATMARAM,MUTHUKAMAN NAGARAJAN,NARAYANA LAKSHMINARAYANA,KHAIRATKAR JOSHI NEELIMA,KATTIGE VIDYA GANAPATI

申请号：

IN2645/MUMNP/2011

公开号：

IN2011MN02645A

申请日:

2011.12.08

申请国别(地区):

IN

年份:

2012

代理人:

摘要：

The present invention relates to tricyclic compounds of formula (I) or pharmaceutically acceptable salt thereof as mPGES-1 inhibitors. These compounds are inhibitors of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and are therefore useful in the treatment of pain and/or inflammation from a variety of diseases or conditions, such as asthama, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases.

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