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Adhesive preparation
专利权人:
Kiyomi Tsuruda;Kouki Shoho;Shinji Yamasoto;Masaru Nakanishi
发明人:
Kiyomi Tsuruda,Shinji Yamasoto,Kouki Shoho,Masaru Nakanishi
申请号:
US12227066
公开号:
US08455376B2
申请日:
2007.08.01
申请国别(地区):
US
年份:
2013
代理人:
摘要:
An adhesive preparation comprising a stretchable support and an adhesive layer laminated on at least one side of the support, whereinthe stretchable support comprises a interlock woven fabric subjected to crimping processing,the adhesive layer contains 10% by mass or more of methyl salicylate with respect to the total mass of the layer,the whole adhesive preparation has moisture permeability of 1 to 350 g/m2·24 hr measured at a temperature of 40° C. and a relative humidity of 90%, andthe methyl salicylate has a plasma AUC0-24 ranging from 3.0 to 60.0 ng·hr/mL in terms of a mean±standard deviation, and salicylic acid as a metabolite of the methyl salicylate has a plasma AUC0-24 ranging from 5000 to 13000 ng·hr/mL in terms of a mean±standard deviation, when the adhesive preparation is applied to a human skin for 8 hours such that an application amount of the adhesive layer applied is 50 to 300 g/m2 and a contact area is 280 cm2.
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