The present invention relates to methods of using AMG 900, a small molecule pan aurora kinase inhibitor, for the treatment of cancer, including solid tumors, hematologically derived tumors and the like. The invention further provides pharmaceutical compositions, dosage ranges and treatment regimens for administering AMG 900 to treat cancer.本發明係關於使用一種小分子泛極光激酶抑制劑AMG 900來治療癌症之方法,該癌症包括實體腫瘤、血液源性腫瘤及其類似癌症。本發明進一步提供用於投與AMG 900來治療癌症之醫藥組合物、劑量範圍及治療方案。