A clamp apparatus for selectively occluding a resilient tube to prevent free flow of fluid in the tube. The device comprises a base member to which the resilient IV tube is attached or through which it passes, and a slide clamp that slides relative to the base member and relative to the tube. The aperture in the slide clamp has a relatively open hole at one end, through which the tube passes when the slide clamp is an open position, allowing fluid to flow through the tube. The aperture also has a relatively constricted slot at the other end, through which the tube passes when the slide clamp is in the occluding position, preventing fluid flow through the tube. A deflectable cantilevered locking arm on the base interlocks with a detent on the slide clamp to lock the slide clamp at the occluding position to avoid inadvertent free flow. A release tab that is used to release the locking arm from the slide clamp is located off center to avoid inadvertent activation. The deflectable arm is unstressed when the slide clamp is in either the occluding or the open positions. A stop device prevents over-stressing the release tab when it is moved. In one embodiment, the clamp apparatus may be slid along the IV tube to a desired location.
