PROBLEM TO BE SOLVED: To provide a pharmaceutical composition which contains a substituted phenanthrene compound with an excellent cancer cell growth inhibitory effect compared with a known substituted phenanthrene compound with a cancer cell growth inhibitory effect.SOLUTION: Disclosed is a pharmaceutical composition which contains a carboxylate compound of a phenanthrene residue having a hydroxyl group and a methoxy group. The composition is effective in prevention and treatment of pancreatic cancer, stomach cancer, colorectal cancer, renal cancer, liver cancer, bone marrow cancer, adrenal cancer, skin cancer, melanoma, lung cancer, small intestinal cancer, prostatic cancer, testis cancer, uterine cancer, breast cancer or ovarian cancer.【課題】公知のがん細胞増殖抑制効果を有する置換フェナントレン化合物と比較して、優れたがん細胞増殖抑制効果を有する置換フェナントレン化合物を含む医薬組成物の提供。【解決手段】水酸基およびメトキシ基を有するフェナントレン残基のカルボン酸エステル化合物を含む医薬組成物。該組成物は、膵臓がん、胃がん、大腸がん、腎臓がん、肝臓がん、骨髄がん、副腎がん、皮膚がん、メラノーマ、肺がん、小腸がん、前立腺がん、精巣がん、子宮がん、乳がんまたは卵巣がんの予防、治療に有効である。【選択図】なし