CAFERRO, Thomas Raymond,CHEN, Zhuoliang,CHO, Young Shin,COSTALES, Abran Q.,LEVELL, Julian Roy,LIU, Gang,MANNING, James R.,SENDZIK, Martin,SHAFER, Cynthia,SHULTZ, Michael David,SUTTON, James,WANG, Yapi
申请号：
HK16101122.1
公开号：
HK1213251A
申请日:
2016.02.01
申请国别(地区):
HK
年份:
2016
代理人:
摘要：
The invention is directed to a formula (I): or a pharmaceutically acceptable salt thereof, wherein R1, R2a, R2b and R3-R7 are herein. The invention is also directed to compositions containing a compound of formula (I) and to the use of such compounds in the inhibition of mutant IDH proteins having a neomorphic activity. The invention is further directed to the use of a compound of formula (I) in the treatment of diseases or disorders associated with such mutant IDH proteins including, but not limited to, cell-proliferation disorders, such as cancer.
