PROBLEM TO BE SOLVED: To provide a stable percutaneously absorbable pharmaceutical preparation for percutaneous administration of selegiline or selegiline hydrochloride, which does not cause a decrease in the cohesive force of the adhesive layer even in the presence of sweat components due to perspiration during wear and which is free from adhesive remaining due to cohesive failure when stripped off.SOLUTION: The percutaneously absorbable pharmaceutical preparation is obtained by forming, on at least one surface of a support, an adhesive layer which contains (-)-(R)-N, &alpha-dimethyl-N-2-propynylphenethylamine and/or its hydrochloride, a metal chloride and an adhesive and is subjected to a crosslinking treatment.COPYRIGHT: (C)2007,JPO&INPIT【課題】セレギリンまたはその塩酸塩を経皮吸収させるための経皮吸収型製剤であって、貼付時の発汗による汗成分の存在下においても粘着剤層の凝集力の低下を生じることはなく剥離除去の際の凝集破壊による糊残りの生じない安定な経皮吸収製剤を提供すること。【解決手段】 (-)-(R)-N,α-ジメチル-N-2-プロピニルフェネチルアミンおよび/またはその塩酸塩、金属塩化物並びに粘着剤を含有し、架橋処理が施されてなる粘着剤層が、支持体の少なくとも片面に形成されてなる経皮吸収製剤。【選択図】なし
