A device and method for marking the location of a tissue biopsy. The device includes a needle with a proximal end, a distal end, a slot disposed adjacent the distal end, and a tip having an opening. The device further includes a handle coupled to the proximal end of the needle, and a cutting apparatus. The cutting apparatus includes a cutting mechanism disposed within the needle and adapted to remove tissue from a target area. The device further includes an ejector mechanism having an ejector rod disposed within the needle and an actuator disposed on the handle and operatively coupled to the ejector rod. The actuator is actuated to eject a marker disposed within the distal end of the needle through one or more of the slot or the opening to mark the location of the tissue biopsy.