UTILISATION DE DERIVES D'IMIDAZOLE ACTIVATEURS D'AMPK, PROCEDE DE PREPARATION DE CES COMPOSES, ET COMPOSITIONS PHARMACEUTIQUES POURVUES DE CEUX-CI

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专利权人:

MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG

发明人:

MOINET, GERARD,MARAIS, DOMINIQUE,HALLAKOU-BOZEC, SOPHIE,CHARON, CHRISTINE

申请号：

CA2657335

公开号：

CA2657335C

申请日:

2007.06.12

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

The invention relates to the use of imidazole derivatives of the formula (I): in which A, R'1, R'2 and R'3 are as defined in the description, as AMPK activators. The invention also relates to processes for the preparation of the said compounds, to their uses for the preparation of medicaments for the treatment of insulin resistance, diabetes and related pathologies, and also obesity, and to the pharmaceutical compositions comprising them. Certain compounds of the formula (I) are novel and, in this respect, also form part of the invention.

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